Current role of LC-MS in therapeutic drug monitoring.
نویسندگان
چکیده
The role of liquid chromatography coupled with mass spectrometry (LC-MS) techniques in routine therapeutic drug monitoring activity is becoming increasingly important. This paper reviews LC-MS methods published in the last few years for certain classes of drugs subject to therapeutic drug monitoring: immunosuppressants, antifungal drugs, antiretroviral drugs, antidepressants and antipsychotics. For each class of compounds, we focussed on the most interesting methods and evaluated the current role of LC-MS in therapeutic drug monitoring.
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ورودعنوان ژورنال:
- Analytical and bioanalytical chemistry
دوره 388 7 شماره
صفحات -
تاریخ انتشار 2007